The iLiNP device : suitable device for precise size control of nanoparticles
Outcomes of basic and theoretical studies created an excellent microfluidic channel having a novel 2D baffle structure suitable for precise size control of nanoparticles (liposomes, lipid micelles, solid lipid nanoparticles, polymer micelles, etc.)
What happens in the iLiNP? Why is the size controllable?
Why is the size control important?
Precise size control is important to boost performance of the particles.
Example: Intrahepatic distribution of siRNAs delivered by the cationic lipid nanoparticles.
Only the 30 nm difference causes the big difference in the distribution of the lipid nanoparticles and/or the inner cargos in vivo.